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. 1999 May;8(5):697-710.
doi: 10.1517/13543784.8.5.697.

Ropinirole in the treatment of Parkinson's disease

T A Zesiewicz  1 , R A Hauser
Affiliations

Ropinirole in the treatment of Parkinson's disease

T A Zesiewicz et al. Expert Opin Investig Drugs. 1999 May.

Abstract

In this review, the pharmacokinetics, safety and tolerability, and clinical efficacy of ropinirole (Requip), a non-ergoline dopamine agonist approved for use in the treatment of Parkinson's disease (PD) are examined. A summary of preclinical and clinical studies is presented. Ropinirole is safe and efficacious as monotherapy in the treatment of early PD and as an adjunct to levodopa in more advanced cases.

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