Limbal allograft, amniotic membrane transplantation, and intraoperative mitomycin C for recurrent pterygium

Abstract

Objective: To conduct a pilot study evaluating the efficacy and safety of limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C treatment for recurrent pterygium.

Design: Prospective, noncomparative, interventional case series.

Participants: Twelve eyes of 11 patients with recurrent pterygium. The mean number of previous surgeries for pterygium was 1.9+/-1.4 (range, 1-6).

Intervention: All subjects received limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C.

Main outcome measures: Pterygium recurrence and complications.

Results: The mean follow-up period was 21.6+/-5.6 months (range, 16-36 months). There was no pterygium recurrence in any of the eyes. Symblepharon reappeared in 3 eyes and diplopia recurred in 2 eyes. There were no other surgical complications and there was no graft rejection.

Conclusions: Limbal allograft, preserved amniotic membrane transplantation, and intraoperative mitomycin C may be a safe and effective procedure for recurrent pterygium.