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Comparative Study
. 2005 Sep 1;21(17):3568-9.
doi: 10.1093/bioinformatics/bti563. Epub 2005 Jun 30.

TICO: a tool for improving predictions of prokaryotic translation initiation sites

Affiliations
Comparative Study

TICO: a tool for improving predictions of prokaryotic translation initiation sites

Maike Tech et al. Bioinformatics. .

Abstract

We provide the tool 'TICO' (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations.

Availability: Our tool can be freely accessed through a web interface at http://tico.gobics.de/

Contact: maike@gobics.de

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