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Review
. 2005 Sep;28(9):453-5.
doi: 10.1016/j.tins.2005.06.007.

SNARE complexes prepare for membrane fusion

Affiliations
Review

SNARE complexes prepare for membrane fusion

Jakob B Sørensen. Trends Neurosci. 2005 Sep.

Abstract

According to a popular theory, the three presynaptic SNARE proteins (syntaxin 1, synaptobrevin 2 and SNAP-25) drive neuroexocytosis by forming a complex that forces vesicle and plasma membranes together. However, individual reactions in this process have been difficult to resolve. Now, two groups have succeeded in studying a very early and a very late step in the fusion process.

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