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Review
. 2005 Aug;8(4):378-84.
doi: 10.1016/j.mib.2005.06.012.

A yeast by any other name: Candida glabrata and its interaction with the host

Rupinder Kaur  1 , Renee Domergue, Margaret L Zupancic, Brendan P Cormack
Affiliations
Review

A yeast by any other name: Candida glabrata and its interaction with the host

Rupinder Kaur et al. Curr Opin Microbiol. 2005 Aug.

Abstract

Well-characterized traits important to Candida albicans virulence, such as hyphal formation or secreted proteinase activity, play no known role in Candida glabrata virulence. Likewise, some C. glabrata characteristics, such as chromatin-based regulation of the large telomeric family of lectins encoded by the EPA (epithelial adhesin) genes, have no precise parallels in C. albicans. However, similarities between the two species, for example in population structure, in the large numbers of (putative) adhesins that they encode, and in phenotypic plasticity conferred by phenotypic switching, suggest that they share general strategies in adaptation to an opportunistic lifestyle.

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