Antibacterial caged-tetraprenylated xanthones from the fruits of Garcinia hanburyi
- PMID: 15997152
- DOI: 10.1248/cpb.53.850
Antibacterial caged-tetraprenylated xanthones from the fruits of Garcinia hanburyi
Abstract
A new caged-tetraprenylated xanthone, hanburinone (1), was isolated from the fresh fruits of Garcinia hanburyi together with four known caged-tetraprenylated xanthones; isomoreollin B (2), morellin (3), moreollic acid (4) and morellic acid (5). Their structures were elucidated by analysis of spectroscopic data and comparison of the NMR data with those reported previously. Compounds 4 and 5 showed moderately antibacterial activity against methicillin-resistant Staphylococcus aureus with a MIC value of 25 microg/ml.
