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. 2005 Jul;43(7):3530-2.
doi: 10.1128/JCM.43.7.3530-3532.2005.

Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?

Bouke C de Jong  1 , Anthony Onipede, Alex S Pym, Sebastien Gagneux, Roxanne S Aga, Kathryn DeRiemer, Peter M Small
Affiliations

Does resistance to pyrazinamide accurately indicate the presence of Mycobacterium bovis?

Bouke C de Jong et al. J Clin Microbiol. 2005 Jul.

Abstract

Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.

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