doi: 10.1016/j.ejpb.2005.03.007.
Flow injection spectrophotometric determination of ofloxacin in pharmaceuticals and urine
Affiliations
- PMID: 16005199
- DOI: 10.1016/j.ejpb.2005.03.007
Item in Clipboard
Flow injection spectrophotometric determination of ofloxacin in pharmaceuticals and urine
Eur J Pharm Biopharm.
2005 Sep.
Abstract
A sensitive and fast flow-injection spectrophotometric method for the determination of ofloxacin is proposed. The method is based on the formation of a yellow complex between ofloxacin and Fe (III), in sulphuric medium. The influence of FI and chemical variables were studied. The calibration graph resulting from measuring the absorbance at 420 nm is linear over the range 5.0 x 10(-6)8.0 x 10(-4)M (1.8-289 mg l(-1)) with a detection limit of 2.0 x 10(-6)M (0.72 mg l(-1)). The method is applied to the routine analysis of ofloxacin in pharmaceuticals and human urine.
Similar articles
-
[Determination of Levofloxacin by chemiluminescence method].Guang Pu Xue Yu Guang Pu Fen Xi. 2004 Apr;24(4):399-401. Guang Pu Xue Yu Guang Pu Fen Xi. 2004. PMID: 15766140 Chinese.
-
Flow-injection determination of cysteine in pharmaceuticals based on luminol-persulphate chemiluminescence detection.Luminescence. 2008 May-Jun;23(3):144-9. doi: 10.1002/bio.1024. Luminescence. 2008. PMID: 18452132
-
Development of novel detection reagent for simple and sensitive determination of trace amounts of formaldehyde and its application to flow injection spectrophotometric analysis.Anal Chim Acta. 2008 Apr 7;612(2):165-72. doi: 10.1016/j.aca.2008.02.028. Epub 2008 Feb 20. Anal Chim Acta. 2008. PMID: 18358862
-
An overview of qualimetric strategies for optimisation and calibration in pharmaceutical analysis using flow injection techniques.Anal Bioanal Chem. 2003 Nov;377(5):863-74. doi: 10.1007/s00216-003-2142-4. Epub 2003 Aug 28. Anal Bioanal Chem. 2003. PMID: 14564437 Review.
-
Recent progress of flow-through optosensing in clinical and pharmaceutical analysis.J Pharm Biomed Anal. 2010 Nov 2;53(3):250-61. doi: 10.1016/j.jpba.2010.04.020. Epub 2010 Apr 20. J Pharm Biomed Anal. 2010. PMID: 20452162 Review.
Cited by
-
Metal complexes of quinolone antibiotics and their applications: an update.Molecules. 2013 Sep 11;18(9):11153-97. doi: 10.3390/molecules180911153. Molecules. 2013. PMID: 24029748 Free PMC article. Review.
-
Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones.Adv Pharm Bull. 2018 Jun;8(2):181-189. doi: 10.15171/apb.2018.022. Epub 2018 Jun 19. Adv Pharm Bull. 2018. PMID: 30023319 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
