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Review
. 2005 Jul-Aug;26(4):217-20.
doi: 10.1159/000086956. Epub 2005 Jul 6.

What makes MUC1 a tumor antigen?

Uwe Karsten  1 , Silvia von Mensdorff-Pouilly, Steffen Goletz
Affiliations
Free article
Review

What makes MUC1 a tumor antigen?

Uwe Karsten et al. Tumour Biol. 2005 Jul-Aug.
Free article

Abstract

The epithelial mucin 1 (MUC1) is an accepted serum tumor marker and cellular tumor antigen. We discuss recent views on the difference(s) between normal and tumor MUC1, and its implication for the development of cancer vaccines and antibody therapies, with special emphasis on the role of glycosylation.

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