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Review
. 2005 Jul 15;122(1):2-4.
doi: 10.1016/j.cell.2005.06.035.

Sugar-coated regulation of T cells

Elizabeth E Eynon  1 , Lauren A Zenewicz, Richard A Flavell
Affiliations
Free article
Review

Sugar-coated regulation of T cells

Elizabeth E Eynon et al. Cell. .
Free article

Abstract

The human gut is host to hundreds of different species of commensal bacteria that live in peaceful partnership with the host immune system. These commensal bacteria are far from neutral bystanders as they are intimately involved in the development of the immune system. Reporting in this issue of Cell, Kasper and colleagues (Mazmanian et al., 2005) reveal that a bacterial polysaccharide, PSA, produced by the commensal bacterium Bacteroides fragilis directs development of the immune system of the mouse host.

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