miRNAs, cancer, and stem cell division
- PMID: 16009126
- DOI: 10.1016/j.cell.2005.06.036
miRNAs, cancer, and stem cell division
Abstract
MicroRNAs (miRNAs) are known to regulate the expression of genes involved in the control of development, proliferation, apoptosis, and the stress response. As a cluster of recent Nature papers now show, altered expression of specific miRNA genes contributes to the initiation and progression of cancer.
Comment on
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A microRNA polycistron as a potential human oncogene.Nature. 2005 Jun 9;435(7043):828-33. doi: 10.1038/nature03552. Nature. 2005. PMID: 15944707 Free PMC article.
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MicroRNA expression profiles classify human cancers.Nature. 2005 Jun 9;435(7043):834-8. doi: 10.1038/nature03702. Nature. 2005. PMID: 15944708
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c-Myc-regulated microRNAs modulate E2F1 expression.Nature. 2005 Jun 9;435(7043):839-43. doi: 10.1038/nature03677. Nature. 2005. PMID: 15944709
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Stem cell division is regulated by the microRNA pathway.Nature. 2005 Jun 16;435(7044):974-8. doi: 10.1038/nature03816. Epub 2005 Jun 8. Nature. 2005. PMID: 15944714
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