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. 1992 Jun;11(6):2055-62.
doi: 10.1002/j.1460-2075.1992.tb05263.x.

A novel extensin that may organize extracellular matrix biogenesis in Volvox carteri

H Ertl  1 , A Hallmann, S Wenzl, M Sumper
Affiliations

A novel extensin that may organize extracellular matrix biogenesis in Volvox carteri

H Ertl et al. EMBO J. 1992 Jun.

Abstract

ISG is a sulphated, extracellular glycoprotein synthesized for only a few minutes in inverting Volvox embryos and inverting sperm cell packets. This control operates at the level of transcription. ISG has been characterized by studies of protein chemistry and electron microscopy. The primary structure of ISG has been derived from genomic DNA and cDNA. ISG is composed of a globular and a rod-shaped domain. The rod-shaped domain represents a member of the extensin family with numerous repeats of Ser-(Hyp)4-6 motifs. A synthetic decapeptide matching the C-terminal sequence is able to disaggregate the organism into individual cells. Immunofluorescence microscopy localizes ISG within the boundary zone of the ECM.

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References

    1. J Mol Biol. 1983 Nov 15;170(4):827-42 - PubMed
    1. Cell. 1986 Aug 15;46(4):633-9 - PubMed
    1. J Cell Biol. 1977 Dec;75(3):719-30 - PubMed
    1. J Cell Sci. 1986 Feb;80:207-31 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Oct;82(19):6551-5 - PubMed

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