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Review
. 2005 Aug 22;100(1-2):72-9.
doi: 10.1016/j.jep.2005.05.011.

Plants as a source of anti-cancer agents

Gordon M Cragg  1 , David J Newman
Affiliations
Review

Plants as a source of anti-cancer agents

Gordon M Cragg et al. J Ethnopharmacol. .

Abstract

Plant-derived compounds have been an important source of several clinically useful anti-cancer agents. These include vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, etoposide, derived from epipodophyllotoxin, and paclitaxel (taxol A number of promising new agents are in clinical development based on selective activity against cancer-related molecular targets, including flavopiridol and combretastin A4 phosphate, while some agents which failed in earlier clinical studies are stimulating renewed interest.

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