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Comment
. 2005 Aug;54(8):1055-9.
doi: 10.1136/gut.2004.053231.

Risks and benefits of azathioprine therapy

D P B McGovern  1 , D P Jewell
Affiliations
Comment

Risks and benefits of azathioprine therapy

D P B McGovern et al. Gut. 2005 Aug.

Abstract

The risk of lymphoma may be increased by about fourfold in patients with inflammatory bowel disease treated with thiopurines. The increased risk could be a result of the medications, the severity of the underlying disease, or a combination of the two.

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References

    1. Kandiel A, Fraser AG, Korelitz BI, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut 2005;54:1121–5. - PMC - PubMed
    1. Loftus E, Tremaine W, Habermann T. Risk of lymphoma in inflammatory bowel disease. Am J Gastroenterol 2000;95:2308–12. - PubMed
    1. Bernstein C, Blanchard J, Kliewer E, et al. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer 2001;91:854–62. - PubMed
    1. Sutherland LR, Ramcharan S, Bryant H, et al. Effect of cigarette smoking on recurrence of Crohn’s disease. Gastroenterology 1990;98:1123–8. - PubMed
    1. Besson H, Renaudier P, Merrill RM, et al. Smoking and non-Hodgkins lymphoma: a case-control study in the Rhone-Alpes region of France. Cancer Causes Control 2003;14:381–9. - PubMed

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