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. 2005 Jun;13(2):63-7.
doi: 10.1080/10647440400025629.

Detection of Candida species in vaginal samples in a clinical laboratory setting

Jason P Trama  1 , Martin E Adelson, Israel Raphaelli, Shlomo M Stemmer, Eli Mordechai
Affiliations

Detection of Candida species in vaginal samples in a clinical laboratory setting

Jason P Trama et al. Infect Dis Obstet Gynecol. 2005 Jun.

Abstract

Objective: To present the detection rates of Candida species in vaginal samples from patients visiting physicians.

Methods: The presence of C. albicans, C. glabrata, C. parapsilosis and C. tropicalis in 3978 vaginal swabs from patients in six US states was detected by PCR amplification.

Results: Candida DNA was detected in 33.1% of the population studied. Of the 1316 positive samples, 80.2% contained C. albicans, 14.3% contained C. glabrata, 5.9% contained C. parapsilosis and 8.0% contained C. tropicalis. Comparing samples by patients' state of residence revealed an association with the detection of C. glabrata (p = 0.029). Comparing samples by patients' age revealed a decrease in the overall detection of Candida (p < 0.001) and C. albicans (p < 0.001), concomitant with an increase in the detection of C. glabrata (p < 0.001) and C. parapsilosis (p = 0.025).

Conclusions: These results provide geographic- and age-specific data on four Candida species associated with vaginitis.

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