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. 2005 Jul;11(7):1086-9.
doi: 10.3201/eid1107.050277.

Adventitious agents and smallpox vaccine in strategic national stockpile

Frederick A Murphy  1 , Bennie I Osburn
Affiliations

Adventitious agents and smallpox vaccine in strategic national stockpile

Frederick A Murphy et al. Emerg Infect Dis. 2005 Jul.

Abstract

In keeping with current standards, we urge that old smallpox vaccines that were made in animal skin and are still a key part of our strategic national stockpile be tested for adventitious infectious agents. The advisory especially applies to viruses that have the potential for zoonotic transmission to human vaccine recipients.

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Figures

Figure
Figure
Freeze-dried (smallpox) vaccine being prepared from virus grown on the skin of a calf. The calf is lying on a grate on a table and is bound to the table. Two men in white coverups, 1 of whom has a surgical mask on his face, are performing a procedure on the calf (scarification and introduction of vaccinia virus into the scarified areas). From the record of the US National Library of Medicine; old negative no. 83-168. WHO/11683 SEARO, Smallpox, Bangladesh, SM 5-1 980. Photograph attributed to J. Mohr, 1980?
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Comment in

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