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. 2005 Jul;11(7):1090-2.
doi: 10.3201/eid1107.040883.

New lymphogranuloma venereum Chlamydia trachomatis variant, Amsterdam

Joke Spaargaren  1 , Han S A Fennema, Servaas A Morré, Henry J C de Vries, Roel A Coutinho
Affiliations

New lymphogranuloma venereum Chlamydia trachomatis variant, Amsterdam

Joke Spaargaren et al. Emerg Infect Dis. 2005 Jul.

Abstract

We retrospectively conducted a study of men who have sex with men who visited the Amsterdam, the Netherlands, sexually transmitted diseases clinic from January 2002 to December 2003 and had rectal Chlamydia trachomatis infections. We found that symptomatic (73%) as well as asymptomatic (43%) patients were infected with a new C. trachomatis LGV variant.

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Figures

Figure
Figure
Schematic representation of the Chlamydia trachomatis ompA gene. In detail, variable segment 2 (VS-2): nucleotide and amino acid (aa) sequence comparison of the prototypes L1, L2, L2´, L2a, and L3 and the newly identified lymphogranuloma venereum (LVG) strain, which we designated L2b. Conserved nucleotides in VS-2 for all LGV strains are shown in red. The nucleotide substitutions in L2b as compared to all LGV strains is indicated by arrows. All aa encoded by the substitution combinations are indicated. CS = constant segment; omp = outer membrane protein.
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