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Review
. 2005 Aug;6(8):657-63.
doi: 10.1038/nrm1697.

Mitochondrial fission in apoptosis

Richard J Youle  1 , Mariusz Karbowski
Affiliations
Review

Mitochondrial fission in apoptosis

Richard J Youle et al. Nat Rev Mol Cell Biol. 2005 Aug.

Abstract

Mitochondria fuse and divide continuously within cells to form a dynamic network. One of the steps in apoptosis is the fragmentation of mitochondria, and recent evidence indicates that the mitochondrial fission machinery actively participates in the process of programmed cell death.

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