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. 2005 May-Jun;12(3):149-57.
doi: 10.1080/10717540590929966.

Pectin gel vehicles for controlled fragrance delivery

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Free article

Pectin gel vehicles for controlled fragrance delivery

LinShu Liu et al. Drug Deliv. 2005 May-Jun.
Free article

Abstract

Using citronellal as a model compound, pectin gels formulations were evaluated for the controlled fragrance release by kinetic and static methods. The pectins with higher degrees of esterification induced a stronger molecular association with the nonpolar fragrance. This resulted in a prolonged duration of fragrance release and the limitation of fragrance adsorption to the receptor skin layers. The increase in pectin concentrations suppressed the fragrance release by a diffusion mechanism. Blocking the carboxyl groups of pectin with calcium ions reduces the hydrophilicity of pectin and provides physical barriers for citronellal diffusion. The pectin/calcium microparticles are promising materials for controlled fragrance release.

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