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Review
. 2005 Nov;81(5):503-12.
doi: 10.1016/j.exer.2005.06.004. Epub 2005 Jul 18.

Mouse mutants as models for congenital retinal disorders

Claudia Dalke  1 , Jochen Graw
Affiliations
Review

Mouse mutants as models for congenital retinal disorders

Claudia Dalke et al. Exp Eye Res. 2005 Nov.

Abstract

Animal models provide a valuable tool for investigating the genetic basis and the pathophysiology of human diseases, and to evaluate therapeutic treatments. To study congenital retinal disorders, mouse mutants have become the most important model organism. Here we review some mouse models, which are related to hereditary disorders (mostly congenital) including retinitis pigmentosa, Leber's congenital amaurosis, macular disorders and optic atrophy.

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