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Review
. 2005 Aug;16(7):691-707.
doi: 10.1097/01.cad.0000167902.53039.5a.

Liposomal encapsulated anti-cancer drugs

Ralf-Dieter Hofheinz  1 , Senta Ulrike Gnad-Vogt, Ulrich Beyer, Andreas Hochhaus
Affiliations
Review

Liposomal encapsulated anti-cancer drugs

Ralf-Dieter Hofheinz et al. Anticancer Drugs. 2005 Aug.

Abstract

Among several drug delivery systems, liposomal encapsulated anti-cancer agents represent an advanced and versatile technology. Several formulations of liposomal anthracyclines are approved, e.g. for the treatment of metastatic breast cancer (pegylated and non-pegylated liposomal doxorubicin) or AIDS-related Kaposi's sarcoma (pegylated liposomal doxorubicin and liposomal daunorubicin). Meanwhile, virtually all anti-cancer drugs have been encapsulated in liposomes using different technologies. This review will summarize preclinical and clinical data of approved and exemplary emerging liposomal anti-cancer agents.

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