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Review
. 2005 Aug;15(4):254-63.
doi: 10.1007/s10286-005-0290-7.

Paraventricular nucleus, stress response, and cardiovascular disease

Eduardo E Benarroch  1
Affiliations
Review

Paraventricular nucleus, stress response, and cardiovascular disease

Eduardo E Benarroch. Clin Auton Res. 2005 Aug.

Abstract

The paraventricular nucleus of the hypothalamus (PVN) is a complex effector structure that initiates endocrine and autonomic responses to stress. It receives inputs from visceral receptors, circulating hormones such as angiotensin II, and limbic circuits and contains neurons that release vasopressin, activate the adrenocortical axis, and activate preganglionic sympathetic or parasympathetic outflows. The neurochemical control of the different subgroups of PVN neurons is complex. The PVN has been implicated in the pathophysiology of congestive heart failure and the metabolic syndrome.

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Comment in

  • Homeostasis and stress.
    Coote JH. Coote JH. Clin Auton Res. 2005 Aug;15(4):247-8. doi: 10.1007/s10286-005-0297-0. Clin Auton Res. 2005. PMID: 16032378 No abstract available.

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