Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2005 Jul;2(7):e219; discussion e225.
doi: 10.1371/journal.pmed.0020219. Epub 2005 Jul 26.

Bitter pills and puffed trials

Stephen Senn
Comment

Bitter pills and puffed trials

Stephen Senn. PLoS Med. 2005 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing Interests: SS has consulted for Actelion, Alcon, Amgen, Astra (now Astra-Zeneca), Astra-Zeneca, Aventis, Auxilium, Biosyn, Boehringer Ingelheim, Bracco, Bristol-Myer Squibb, Chiesi, Chiron, Ciba-Geigy (now Novartis), Covance, Dexcel, Elan, Eli-Lilly, Fournier, Glaxo-Wellcome (now GSK), GSK, INO Therapeutics, Janssen, Johnson&Johnson, Jouveinal (now Pfizer), Leiras, Merz, Novartis, Novartis Consumer Health, Novartis Ophthamology, Numico, Orion, Pleaid, Pfizer, Pharmacia (now Pfizer), Pharmapart, Phocus, Roche, Sandoz (now Novartis), Sanofi, Servier, Schein, Schering AG, Shire, Smith-Kline Beecham (now GSK), Statwood, Strakan, Wyeth, Zeneca (now Astra-Zeneca) and possibly other companies he has forgotten about. He used to work for Ciba-Geigy and in consequence owns some shares in Novartis. This note has been prepared without consulting any of the above companies, without their knowledge, and without their express permission, and none of his views should be attributed to any of the above. SS is an academic whose career is furthered by publishing. His views should also not be ascribed to his current employer, Glasgow University.

Comment on

Similar articles

See all similar articles

References

    1. Smith R. Medical journals are an extension of the marketing arm of pharmaceutical companies. PLoS Med. 2005;2:e138. doi: 10.1371/journal.pmed.0020138. - DOI - PMC - PubMed
    1. Senn SJ. Authorship of drug industry trials. Pharm Stat. 2002;1:5–7.
    1. ICH harmonised tripartite guideline. Statistical principles for clinical trials. International Conference on Harmonisation E9 Expert Working Group. Stat Med. 1999;18:1905–1942. - PubMed
    1. Jones B, Jarvis P, Lewis JA, Ebbutt AF. Trials to assess equivalence: The importance of rigorous methods. BMJ. 1996;313:36–39. - PMC - PubMed
    1. International Conference on Harmonisation. ICH harmonised tripartite guideline: Choice of control group and related issues in clinical trials E10. 2000 Available: http://www.ich.org/MediaServer.jser?@_ID=486&@_MODE=GLB. Accessed 6 June 2005.