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Review
. 2005 Jul;23(1):1-2.
doi: 10.1016/j.immuni.2005.07.001.

Divide and conquer: division of labor by B-1 B cells

Kishore R Alugupalli  1 , Rachel M Gerstein
Affiliations
Free article
Review

Divide and conquer: division of labor by B-1 B cells

Kishore R Alugupalli et al. Immunity. 2005 Jul.
Free article

Abstract

Capsular polysaccharides enhance bacterial virulence. In this issue of Immunity, demonstrate a division of labor between the B-1 B cell subsets: natural antibodies from B-1a cells limit infection by Streptococcus pneumoniae, whereas B-1b cells generate the anticapsule-induced response that prevents fatal infection.

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