Case Reports
doi: 10.1002/ajh.20349.
Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma
Affiliations
- PMID: 16044441
- DOI: 10.1002/ajh.20349
Item in Clipboard
Case Reports
Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma
Am J Hematol.
2005 Aug.
Free article
Abstract
We report a patient with adult T-cell lymphoma who developed acute myeloid leukemia (AML) after allogeneic cord blood transplantation (CBT). Fluorescence in situ hybridization (FISH) studies and molecular analysis using short tandem repeat (STR) sequences proved the AML to be of donor origin. Although 25 cases of donor cell leukemia (DCL) occurring after allogeneic bone marrow transplantation have previously been reported, there have been no reports of DCL after CBT. This case is the first-reported DCL patient after CBT.
Copyright (c) 2005 Wiley-Liss, Inc.
Similar articles
-
Acute myeloid leukemia of donor origin after allogeneic bone marrow transplantation for precursor T-cell acute lymphoblastic leukemia: case report and review of the literature.Am J Hematol. 2006 Mar;81(3):178-85. doi: 10.1002/ajh.20389. Am J Hematol. 2006. PMID: 16493618
-
Acute myeloid leukaemia of donor cell origin developing 5 years after allogeneic bone marrow transplantation for chronic myeloid leukaemia.Bone Marrow Transplant. 2002 Mar;29(5):449-52. doi: 10.1038/sj.bmt.1703378. Bone Marrow Transplant. 2002. PMID: 11919736
-
Need for an accurate molecular diagnosis to assess the donor origin of leukemia relapse after allogeneic stem cell transplantation.Haematologica. 2000 Nov;85(11):1153-7. Haematologica. 2000. PMID: 11064467
-
Donor cell-derived leukemias/myelodysplastic neoplasms in allogeneic hematopoietic stem cell transplant recipients: a clinicopathologic study of 10 cases and a comprehensive review of the literature.Am J Clin Pathol. 2011 Apr;135(4):525-40. doi: 10.1309/AJCPPJUQ9DNR1GHP. Am J Clin Pathol. 2011. PMID: 21411775 Review.
-
Donor cell leukemia: a review.Biol Blood Marrow Transplant. 2011 Jun;17(6):771-89. doi: 10.1016/j.bbmt.2010.10.010. Epub 2010 Oct 15. Biol Blood Marrow Transplant. 2011. PMID: 20951819 Review.
Cited by
-
Genetics of donor cell leukemia in acute myelogenous leukemia and myelodysplastic syndrome.Bone Marrow Transplant. 2021 Jul;56(7):1535-1549. doi: 10.1038/s41409-021-01214-z. Epub 2021 Mar 8. Bone Marrow Transplant. 2021. PMID: 33686252 Review.
-
Risks and mechanisms of oncological disease following stem cell transplantation.Stem Cell Rev Rep. 2010 Sep;6(3):411-24. doi: 10.1007/s12015-010-9134-5. Stem Cell Rev Rep. 2010. PMID: 20300888 Review.
-
Donor-derived myelodysplastic syndrome and acute leukaemia after allogeneic haematopoietic stem cell transplantation: incidence, natural history and treatment response.Br J Haematol. 2014 Jul;166(2):209-12. doi: 10.1111/bjh.12847. Epub 2014 Mar 25. Br J Haematol. 2014. PMID: 24661075 Free PMC article.
-
Alternative haematopoietic stem cell sources for transplantation: place of umbilical cord blood.Br J Haematol. 2009 Oct;147(2):246-61. doi: 10.1111/j.1365-2141.2009.07828.x. Br J Haematol. 2009. PMID: 19796274 Free PMC article. Review.
-
Donor cell-derived leukemia after cord blood transplantation and a review of the literature: differences between cord blood and BM as the transplant source.Bone Marrow Transplant. 2014 Jan;49(1):102-9. doi: 10.1038/bmt.2013.127. Epub 2013 Sep 9. Bone Marrow Transplant. 2014. PMID: 24013690 Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
