Review
doi: 10.1111/j.0105-2896.2005.00294.x.
Innate and adaptive immunity: the yin and yang of celiac disease
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- PMID: 16048552
- DOI: 10.1111/j.0105-2896.2005.00294.x
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Review
Innate and adaptive immunity: the yin and yang of celiac disease
Immunol Rev.
2005 Aug.
Abstract
Celiac disease is a multigenetic complex inflammatory disorder with an autoimmune component, induced by gluten, a protein found in wheat. It is a unique human disease model to dissect the innate and adaptive immune mechanisms underlying T-cell-mediated tissue destruction and the development of T-cell lymphoma in conditions of chronic T-cell activation.
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