Case Reports
doi: 10.1016/0002-9343(92)90789-e.
Chronic inflammatory arthritis after treatment with high-dose interleukin-2 for malignancy
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- PMID: 1605152
- DOI: 10.1016/0002-9343(92)90789-e
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Case Reports
Chronic inflammatory arthritis after treatment with high-dose interleukin-2 for malignancy
Am J Med.
1992 Jun.
Abstract
Interleukin-2 (IL-2) immunotherapy resulted in the development of inflammatory arthritis in three male patients with metastatic cancer. Two patients developed a clinical picture consistent with rheumatoid arthritis. A third patient with a remote history of Reiter's syndrome developed a recrudescence of an inflammatory arthritis after treatment with IL-2. The clinical, laboratory, and histologic data on the patients and the potential pathophysiologic mechanisms are discussed.
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