Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Aug 7;11(29):4600-3.
doi: 10.3748/wjg.v11.i29.4600.

Clinical characteristics of fulminant hepatitis in pregnancy

Xiao-Mao Li  1 , Lin Ma, Yue-Bo Yang, Zhong-Jie Shi, Shui-Sheng Zhou
Affiliations

Clinical characteristics of fulminant hepatitis in pregnancy

Xiao-Mao Li et al. World J Gastroenterol. .

Abstract

Aim: To investigate the clinical characteristics of fulminant hepatitis in pregnancy.

Methods: We compared and analyzed the etiology, clinical characteristics, and laboratory examinations of 25 cases of fulminant hepatitis in pregnancy and 30 cases of fulminant hepatitis not in pregnancy.

Results: HBV infection and chronic fulminant hepatitis were most common both in the pregnant and in the non-pregnant groups. Jaundice, digestive tract symptoms, increase of bilirubin and thrombinogen activity were the main manifestations. The incidence of hepatic encephalopathy (HE) and hepato-renal syndrome (HRS) was significantly different between the two groups. The incidence of preterm labor, dead fetus and neonatal asphyxia was high.

Conclusion: Fulminant hepatitis is likely to occur in late pregnancy with more severe complications, which significantly influences maternity, perinatal fetus, and newborn.

PubMed Disclaimer

References

    1. Cao ZY. Chinese Obstetrics and Gynecology. Beijin: People's Medical Publishing House; 1999. p. 486.
    1. Infectious diseases branch, parasitic diseases branch and liver disease branch of Chinese Medical Association. Prevention and cure program for viral hepatitis. Zhonghua Ganzangbing Zazhi. 2000;8:324–329.
    1. Li XM, Liu SL, Li X, Huang HJ, Lu JX, Gao ZL. The relative study of hepatitise B virus DNA in maternal blood umbilical blood and breast milk. Zhongshan Yike Daxue Xuebao. 2000;21:233–235.
    1. Merle P, Trépo C, Zoulim F. Current management strategies for hepatitis B in the elderly. Drugs Aging. 2001;18:725–735. - PubMed
    1. Hamdani-Belghiti S, Bouazzaou NL. [Mother-child transmission of hepatitis B virus. State of the problem and prevention] Arch Pediatr. 2000;7:879–882. - PubMed