Comment
doi: 10.1016/j.cmet.2005.01.009.
ABCG1: how critical for cholesterol transport?
Affiliations
- PMID: 16054048
- DOI: 10.1016/j.cmet.2005.01.009
Item in Clipboard
Comment
ABCG1: how critical for cholesterol transport?
Cell Metab.
2005 Feb.
Abstract
In the current issue of Cell Metabolism, Kennedy et al. (2005) have extended our understanding of the ABCG1 transporter. Their studies demonstrate that, at least in macrophages, ABCG1 is responsible for much of the cholesterol efflux that utilizes mature HDL as an acceptor.
Comment on
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ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation.Cell Metab. 2005 Feb;1(2):121-31. doi: 10.1016/j.cmet.2005.01.002. Cell Metab. 2005. PMID: 16054053