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Review
. 2005 Mar;1(3):155-7.
doi: 10.1016/j.cmet.2005.02.005.

Cellular iron: ferroportin is the only way out

Tomas Ganz  1
Affiliations
Free article
Review

Cellular iron: ferroportin is the only way out

Tomas Ganz. Cell Metab. 2005 Mar.
Free article

Abstract

Ferroportin is the sole cellular efflux channel for iron and is regulated by the iron regulatory hormone hepcidin, which binds ferroportin and induces its internalization and degradation. New studies of ferroportin knockout mice define a key role for this transporter in physiological iron balance.

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