Review
doi: 10.1016/j.cmet.2005.02.005.
Cellular iron: ferroportin is the only way out
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- PMID: 16054057
- DOI: 10.1016/j.cmet.2005.02.005
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Review
Cellular iron: ferroportin is the only way out
Cell Metab.
2005 Mar.
Free article
Abstract
Ferroportin is the sole cellular efflux channel for iron and is regulated by the iron regulatory hormone hepcidin, which binds ferroportin and induces its internalization and degradation. New studies of ferroportin knockout mice define a key role for this transporter in physiological iron balance.
Comment on
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The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis.Cell Metab. 2005 Mar;1(3):191-200. doi: 10.1016/j.cmet.2005.01.003. Cell Metab. 2005. PMID: 16054062
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