The prepared mind of the worm
- PMID: 16054058
- DOI: 10.1016/j.cmet.2005.02.004
The prepared mind of the worm
Abstract
In C. elegans, dauer pheromone is an indicator of population density and influences pathways that regulate metabolism, development, and aging. In a recent publication in Nature, Paik and coworkers (Jeong at al., 2005) show the purified substance to be a pyran ring conjugated to heptanoic acid, setting the stage for dissecting downstream signaling pathways.
Comment on
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Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone.Nature. 2005 Feb 3;433(7025):541-5. doi: 10.1038/nature03201. Nature. 2005. PMID: 15690045
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