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Review
. 2005 May;1(5):287-8.
doi: 10.1016/j.cmet.2005.04.009.

AMPK and p53 help cells through lean times

Carson C Thoreen  1 , David M Sabatini
Affiliations
Free article
Review

AMPK and p53 help cells through lean times

Carson C Thoreen et al. Cell Metab. 2005 May.
Free article

Abstract

Cells that encounter low nutrient conditions often respond by arresting cell division or becoming apoptotic. Recent work by Jones and colleagues (Jones et al.,2005) reveals how the AMP-activated kinase mediates this process by phosphorylating and activating the tumor suppressor p53.

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