Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 May;1(5):293-6.
doi: 10.1016/j.cmet.2005.04.001.

Kisspeptins and GPR54--the new biology of the mammalian GnRH axis

Samuel A J R Aparicio  1
Affiliations
Free article
Review

Kisspeptins and GPR54--the new biology of the mammalian GnRH axis

Samuel A J R Aparicio. Cell Metab. 2005 May.
Free article

Abstract

Recent genetic evidence in humans and from mouse knockouts has linked kisspeptin-driven GPR54 signaling to the regulation of GnRH release from the hypothalamus. These molecules appear to represent a previously unsuspected control point for GnRH secretion, with important implications for the biology and pathology of the sex steroid axis.

PubMed Disclaimer

LinkOut - more resources