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Editorial
. 2005 Aug;25(8):1536-40.
doi: 10.1161/01.ATV.0000174795.62387.d3.

Lipoprotein retention--and clues for atheroma regression

Kevin Jon Williams, Ira Tabas
Editorial

Lipoprotein retention--and clues for atheroma regression

Kevin Jon Williams et al. Arterioscler Thromb Vasc Biol. 2005 Aug.

Abstract

Subendothelial retention of apoB-lipoproteins is the key initiating event in atherosclerosis, provoking a cascade of pathogenic responses. Dissection of the molecular participants provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids derived from retained lipoproteins may be crucial in promoting beneficial remodeling of lesions.

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