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Editorial
. 2005 Aug:187:101-2.
doi: 10.1192/bjp.187.2.101.

Social defeat: risk factor for schizophrenia?

Jean-Paul Selten, Elizabeth Cantor-Graae
Editorial

Social defeat: risk factor for schizophrenia?

Jean-Paul Selten et al. Br J Psychiatry. 2005 Aug.

Abstract

The hypothesis that chronic and long-term experience of 'social defeat' may increase the risk for schizophrenia is proposed. This increased risk may result from sensitisation of the mesolimbic dopamine system and/or increased baseline activity of this system. Data supporting the social defeat hypothesis are presented.

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Comment in

  • Social defeat and schizophrenia.
    Cantor C. Cantor C. Br J Psychiatry. 2006 Apr;188:393-4; author reply 394. doi: 10.1192/bjp.188.4.393-a. Br J Psychiatry. 2006. PMID: 16582069 No abstract available.
  • Social defeat and schizophrenia.
    Price JS. Price JS. Br J Psychiatry. 2006 Apr;188:393; author reply 394. doi: 10.1192/bjp.188.4.393. Br J Psychiatry. 2006. PMID: 16582070 No abstract available.

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