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Comparative Study
. 1992 Feb;36(2):470-2.
doi: 10.1128/AAC.36.2.470.

Use of fluoroquinolones for prophylaxis of murine Pneumocystis carinii pneumonia

M Brun-Pascaud  1 , M Fay, M Zhong, J Bauchet, A Dux-Guyot, J J Pocidalo
Affiliations
Comparative Study

Use of fluoroquinolones for prophylaxis of murine Pneumocystis carinii pneumonia

M Brun-Pascaud et al. Antimicrob Agents Chemother. 1992 Feb.

Abstract

We compared the prophylactic activities of six fluoroquinolones against Pneumocystis carinii pneumonia in immunosuppressed rats. Pefloxacin was the only agent which was as effective as the reference drug trimethoprim-sulfamethoxazole. Clinical trials with pefloxacin in patients at risk for P. carinii pneumonia appear to be justified.

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References

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    1. Antimicrob Agents Chemother. 1985 Oct;28(4):581-6 - PubMed
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