This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Comment

. 2005 Oct;146(4):479-80.

doi: 10.1038/sj.bjp.0706364.

Reduced vascular reactivity after chronic nitroglycerine administration: EDHF mechanism is also downregulated

Pierre-Yves von der Weid¹, Harold A Coleman

Affiliations

Affiliation

¹ Mucosal Inflammation and Smooth Muscle Research Groups, Department of Physiology & Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. vonderwe@ucalgary.ca

PMID: 16056231
PMCID: PMC1751182
DOI: 10.1038/sj.bjp.0706364

Comment

Reduced vascular reactivity after chronic nitroglycerine administration: EDHF mechanism is also downregulated

Pierre-Yves von der Weid et al. Br J Pharmacol. 2005 Oct.

. 2005 Oct;146(4):479-80.

doi: 10.1038/sj.bjp.0706364.

Authors

Pierre-Yves von der Weid¹, Harold A Coleman

Affiliation

¹ Mucosal Inflammation and Smooth Muscle Research Groups, Department of Physiology & Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada. vonderwe@ucalgary.ca

PMID: 16056231
PMCID: PMC1751182
DOI: 10.1038/sj.bjp.0706364

No abstract available

PubMed Disclaimer

Comment on

Reduced hyperpolarization in endothelial cells of rabbit aortic valve following chronic nitroglycerine administration.
Kusama N, Kajikuri J, Yamamoto T, Watanabe Y, Suzuki Y, Katsuya H, Itoh T. Kusama N, et al. Br J Pharmacol. 2005 Oct;146(4):487-97. doi: 10.1038/sj.bjp.0706363. Br J Pharmacol. 2005. PMID: 16056232 Free PMC article.

Similar articles

Reduced hyperpolarization in endothelial cells of rabbit aortic valve following chronic nitroglycerine administration.
Kusama N, Kajikuri J, Yamamoto T, Watanabe Y, Suzuki Y, Katsuya H, Itoh T. Kusama N, et al. Br J Pharmacol. 2005 Oct;146(4):487-97. doi: 10.1038/sj.bjp.0706363. Br J Pharmacol. 2005. PMID: 16056232 Free PMC article.
Vascular tolerance to nitroglycerin in ascorbate deficiency: results are in favour of an important role of oxidative stress in nitrate tolerance.
Daiber A, Gori T. Daiber A, et al. Cardiovasc Res. 2008 Sep 1;79(4):722-3; author reply 724. doi: 10.1093/cvr/cvn174. Epub 2008 Jun 25. Cardiovasc Res. 2008. PMID: 18583336 No abstract available.
EDHF-mediated rapid restoration of hypotensive response to acetylcholine after chronic, but not acute, nitric oxide synthase inhibition in rats.
Desai KM, Gopalakrishnan V, Hiebert LM, McNeill JR, Wilson TW. Desai KM, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):120-6. doi: 10.1016/j.ejphar.2006.06.072. Epub 2006 Jul 5. Eur J Pharmacol. 2006. PMID: 16876156
New insights into nitroglycerin effects and tolerance: role of calcitonin gene-related peptide.
Peng J, Li YJ. Peng J, et al. Eur J Pharmacol. 2008 May 31;586(1-3):9-13. doi: 10.1016/j.ejphar.2008.02.039. Epub 2008 Mar 4. Eur J Pharmacol. 2008. PMID: 18367169 Review.
Contribution of endothelium-derived hyperpolarizing factors to the regulation of vascular tone in humans.
Bellien J, Thuillez C, Joannides R. Bellien J, et al. Fundam Clin Pharmacol. 2008 Aug;22(4):363-77. doi: 10.1111/j.1472-8206.2008.00610.x. Fundam Clin Pharmacol. 2008. PMID: 18705747 Review.

See all similar articles

Cited by

The role of vascular endothelium in nitroglycerin-mediated vasodilation.
Zhou K, Parker JD. Zhou K, et al. Br J Clin Pharmacol. 2019 Feb;85(2):377-384. doi: 10.1111/bcp.13804. Epub 2018 Dec 3. Br J Clin Pharmacol. 2019. PMID: 30378151 Free PMC article. Clinical Trial.
Effects of chronic in vivo administration of nitroglycerine on ACh-induced endothelium-dependent relaxation in rabbit cerebral arteries.
Watanabe Y, Kusama N, Itoh T. Watanabe Y, et al. Br J Pharmacol. 2008 Jan;153(1):132-9. doi: 10.1038/sj.bjp.0707562. Epub 2007 Oct 29. Br J Pharmacol. 2008. PMID: 17965730 Free PMC article.

References

1. ALLEN T., IFTINCA M., COLE W.C., PLANE F. Smooth muscle membrane potential modulates endothelium-dependent relaxation of rat basilar artery via myo-endothelial gap junctions. J. Physiol. 2002;545:975–986. - PMC - PubMed
1. BAUERSACHS J., POPP R., HECKER M., SAUER E., FLEMING I., BUSSE R. Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation. 1996;94:3341–3347. - PubMed
1. CHEN G., SUZUKI H., WESTON A.H. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br. J. Pharmacol. 1988;95:1165–1174. - PMC - PubMed
1. CHUNG S.J., FUNG H.L. Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells. J. Pharmacol. Exp. Ther. 1990;253:614–619. - PubMed
1. COLEMAN H.A., TARE M., PARKINGTON H.C. Endothelial potassium channels, endothelium-dependent hyperpolarization and the regulation of vascular tone in health and disease. Clin. Exp. Pharmacol. Physiol. 2004;31:641–649. - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources