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Review
. 1992 Apr;4(2):189-94.
doi: 10.1016/0952-7915(92)90012-4.

Embryonic stem cells and homologous recombination

W P Fung-Leung  1 , T W Mak
Affiliations
Review

Embryonic stem cells and homologous recombination

W P Fung-Leung et al. Curr Opin Immunol. 1992 Apr.

Abstract

Mice with defined genetic defects can now be generated using gene targeting technology based on the successful generation of mouse embryonic stem cells with the potential for germ line transmission, and the development of methods for detection of homologous recombination.

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