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Review
. 2005 Aug 9;102(32):11129-30.
doi: 10.1073/pnas.0505073102. Epub 2005 Aug 1.

Mast cell-committed progenitors

Yukihiko Kitamura  1 , Akihiko Ito
Affiliations
Review

Mast cell-committed progenitors

Yukihiko Kitamura et al. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Change of lineage model of hematopoiesis. (A) In the old view, the presence of MCPs was not clear, but mast cells were considered to be the progeny of CMPs without convincing evidence. Therefore, MCP is put in brackets. (B) In the new view proposed by Chen et al. (4), the presence of MCPs is clear, and MCPs are directly derived from MPPs. The thick line shows the main differentiation route from MPP to mast cell. CLP, common lymphoid progenitor; CMP, common myeloid progenitor; GMP, granulocyte/macrophage progenitor; MCP, mast cell-committed progenitor; MEP, megakaryocyte/erythrocyte progenitor; MPP, multipotential progenitor.
See this image and copyright information in PMC

Comment on

  • Identification of mast cell progenitors in adult mice.
    Chen CC, Grimbaldeston MA, Tsai M, Weissman IL, Galli SJ. Chen CC, et al. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11408-13. doi: 10.1073/pnas.0504197102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006518 Free PMC article.

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