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Case Reports
. 2005 Jul-Aug;28(4):188-90.
doi: 10.1097/01.wnf.0000169732.00690.32.

Levetiracetam-induced parkinsonism in a Huntington disease patient

Theresa A Zesiewicz  1 , Juan Sanchez-Ramos, Kelly L Sullivan, Robert A Hauser
Affiliations
Case Reports

Levetiracetam-induced parkinsonism in a Huntington disease patient

Theresa A Zesiewicz et al. Clin Neuropharmacol. 2005 Jul-Aug.

Abstract

The authors present a man with Huntington disease who was treated with levetiracetam (Keppra) in an effort to reduce chorea. Chorea was markedly reduced, but the patient developed parkinsonism and lethargy after 6 weeks of treatment. Symptoms consisted of resting tremor, rigidity, increased dystonia, and gait difficulty. Side effects from levetiracetam resolved completely within 7 days of levetiracetam discontinuation, and chorea returned to baseline.

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