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Review
. 2005 Aug;6(8):635-45.
doi: 10.1038/nrm1703.

Transcriptional regulation and transformation by Myc proteins

Sovana Adhikary  1 , Martin Eilers
Affiliations
Review

Transcriptional regulation and transformation by Myc proteins

Sovana Adhikary et al. Nat Rev Mol Cell Biol. 2005 Aug.

Abstract

Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.

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