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. 1979 May 31;279(5712):396-400.
doi: 10.1038/279396a0.

Regulatory functions of the lambda repressor reside in the amino-terminal domain

R T Sauer, C O Pabo, B J Meyer, M Ptashne, K C Backman

Regulatory functions of the lambda repressor reside in the amino-terminal domain

R T Sauer et al. Nature. .

Abstract

The repressor of bacteriophage lambda is a protein containing two domains of approximately equal size. Fragments containing the amino-terminal domain of repressor bind specifically to lambda operator DNA and mediate positive and negative control of lambda transcription both in vitro and in vivo.

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