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. 2005 Sep 1;41(5):754-7.
doi: 10.1086/432583. Epub 2005 Jul 20.

Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Andrea L H Kwa  1 , ChinSiew Loh, Jenny G H Low, Asok Kurup, Vincent H Tam
Affiliations

Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

Andrea L H Kwa et al. Clin Infect Dis. .

Abstract

Twenty-one patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa pneumonia were treated with nebulized polymyxin E (colistin). Overall clinical and microbiological response rates were 57.1% and 85.7%, respectively. Nebulized colistin may be reasonably efficacious and safe for treatment of MDR pneumonia. Its role in therapy warrants further investigation in comparative studies.

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