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Review
. 2005 Aug;19(4):665-87, vi-vii.
doi: 10.1016/j.hoc.2005.05.004.

AIDS-related primary central nervous system lymphoma

Yvette L Kasamon  1 , Richard F Ambinder
Affiliations
Review

AIDS-related primary central nervous system lymphoma

Yvette L Kasamon et al. Hematol Oncol Clin North Am. 2005 Aug.

Abstract

Primary central nervous system lymphoma (PCNSL) can develop in the setting of profound immunosuppression, including late-stage infection with HIV. The management of such patients has yet to be defined optimally and differs substantially from that of immunocompetent patients who have PCNSL. The clinical features, diagnosis, and management of AIDS-related PCNSL are reviewed. The authors focus on commonly encountered diagnostic and therapeutic dilemmas and explore some promises and pitfalls of Epstein-Barr virus-directed therapies.

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