Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2005 Aug;14(3):145-51.
doi: 10.1053/j.sempedsurg.2005.05.002.

The role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitis

Michael S Caplan  1 , Dyan Simon, Tamas Jilling
Affiliations
Review

The role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitis

Michael S Caplan et al. Semin Pediatr Surg. 2005 Aug.

Abstract

The pathogenesis of neonatal necrotizing enterocolitis remains poorly understood. Recent evidence suggests that PAF (platelet activating factor) and human toll-like receptors (TLRs) contribute to the pro-inflammatory response that is characteristic of NEC pathology. Understanding the regulation of these molecular interactions may provide new approaches for prevention or treatment of this dreaded condition.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources