Review
doi: 10.1053/j.sempedsurg.2005.05.002.
The role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitis
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- PMID: 16084401
- DOI: 10.1053/j.sempedsurg.2005.05.002
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Review
The role of PAF, TLR, and the inflammatory response in neonatal necrotizing enterocolitis
Semin Pediatr Surg.
2005 Aug.
Abstract
The pathogenesis of neonatal necrotizing enterocolitis remains poorly understood. Recent evidence suggests that PAF (platelet activating factor) and human toll-like receptors (TLRs) contribute to the pro-inflammatory response that is characteristic of NEC pathology. Understanding the regulation of these molecular interactions may provide new approaches for prevention or treatment of this dreaded condition.
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