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Randomized Controlled Trial
. 2005 Aug 9;65(3):444-7.
doi: 10.1212/01.wnl.0000168259.94991.8a.

A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster

James D Berry  1 , Karin Lottrup Petersen
Affiliations
Randomized Controlled Trial

A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster

James D Berry et al. Neurology. .

Abstract

This randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.

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