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. 2005 May 20;94(19):196101.
doi: 10.1103/PhysRevLett.94.196101. Epub 2005 May 16.

Statics and dynamics of single DNA molecules confined in nanochannels

Walter Reisner  1 , Keith J Morton, Robert Riehn, Yan Mei Wang, Zhaoning Yu, Michael Rosen, James C Sturm, Stephen Y Chou, Erwin Frey, Robert H Austin
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Free article

Statics and dynamics of single DNA molecules confined in nanochannels

Walter Reisner et al. Phys Rev Lett. .
Free article

Abstract

The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.

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