Activities of four glycolytic enzymes (HK, PFK, PK, and LDH) and isozymic pattern of LDH in mouse lung tumor induced by urethan
- PMID: 160915
- PMCID: PMC12253788
- DOI: 10.1007/BF00410650
Activities of four glycolytic enzymes (HK, PFK, PK, and LDH) and isozymic pattern of LDH in mouse lung tumor induced by urethan
Abstract
In the lungs of CFLP mice the activities of glycolytic key enzymes (HK, PFK, PK) and LDH as well as LDH isozymic pattern change in the course of life. The activities of these glycolytic enzymes in the lung tumors induced by urethan in CFLP mice are significantly higher than those in the normal adult lung and they are similar to those in the normal fetal lung. The isozymic pattern of LDH of pulmonary adenomas resembles that of the normal fetal lung, too.
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References
-
- Boján, F., Dauda, G.: Az uretán carcinogen hatásának tanulmányozása I (in Hungarian). Magyar Onkologia 20, 232–237 (1976)
-
- Dietz, A.A., Lubrano, T.: Separation and quantitation of LDH isoenzymes by disc electrophoresis. Anal. Biochem. 20, 246–257 (1967) - PubMed
-
- Goldberg, E.: Lactic and malic dehydrogenase in human spermatozoa. Science 139, 602–603 (1963) - PubMed
-
- Guttman, I., Bernt, E.: Pyruvate kinase. In: Methoden der enzymatischen Analyse. Bergmeyer, H.U. (ed.), Vol. 1, pp. 800–803. Weinheim: Verlag Chemie 1974
-
- Heumann, S., Falkenberg, F., Pfleiderer, G.: Purification and immunological characterization of the human hexokinase isoenzymes I and III. Biochim. Biophys. Acta 334, 328–342 (1974)
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