Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Aug 14;11(30):4685-8.
doi: 10.3748/wjg.v11.i30.4685.

Changing patterns of colorectal cancer in China over a period of 20 years

Ming Li  1 , Jin Gu
Affiliations

Changing patterns of colorectal cancer in China over a period of 20 years

Ming Li et al. World J Gastroenterol. .

Abstract

Aim: To determine whether any changes have occurred on the patterns of colorectal cancer in China.

Methods: Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology.

Results: From 1980s to 1990s, the mean age of the colorectal cancer patients has increased. The percentage of the female patients rose. The distribution of colorectal carcinoma shows a predominance of rectal cancer. However, the proportion of proximal colon cancer (including transverse and ascending colon) increased significantly accompanied by a decline in the percentage of rectal cancer. Similarity in the percentage of distal colon cancer between two decades was revealed. In the 1990s, statistically more Stage B patients were found than those in 1980s. In addition, databases show a significant decrease in the Stage D cases. The proportion of adenocarcinoma increased, but the mucinous adenocarcinoma decreased during two decades.

Conclusion: These findings indicate that the pattern of colorectal cancer in China has been changing. Especially, a proximal shift due to the increasing proportion of ascending and transverse colon cancer has occurred in China.

PubMed Disclaimer

References

    1. Pisani P, Parkin DM, Bray F, Ferlay J. Erratum: Estimates of the worldwide mortality from 25 cancers in 1990. Int. J. Cancer, 83, 18-29 (1999) Int J Cancer. 1999;83:870–873. doi: 10.1002/(SICI)1097-0215(19990924)83:1<18::AID-IJC5>3.0.CO;2-M. - DOI - PubMed
    1. Burt RW, DiSario JA, Cannon-Albright L. Genetics of colon cancer: impact of inheritance on colon cancer risk. Annu Rev Med. 1995;46:371–379. doi: 10.1146/annurev.med.46.1.371. - DOI - PubMed
    1. Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin. 2001;51:15–36. doi: 10.3322/canjclin.51.1.15. - DOI - PubMed
    1. Zheng S. Recent study on colorectal cancer in China: early detection and novel related gene. Chin Med J (Engl) 1997;110:309–310. - PubMed
    1. The information center on health statistics of Ministry of Health P.R China. 2002, 4 Beijing