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. 2005 Aug 19;70(17):6980-3.
doi: 10.1021/jo050908d.

Palladium-catalyzed one-pot synthesis of highly substituted furans by a three-component annulation reaction

Xin-hua Duan  1 , Xue-yuan Liu, Li-na Guo, Meng-chun Liao, Wei-Min Liu, Yong-min Liang
Affiliations

Palladium-catalyzed one-pot synthesis of highly substituted furans by a three-component annulation reaction

Xin-hua Duan et al. J Org Chem. .

Abstract

A new three-component cyclization-coupling reaction catalyzed by palladium was developed, producing polysubstituted furans in good yields from readily available substrates. The reaction conditions and the scope of the process were examined, and a possible mechanism is proposed.

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